To date, more than 13,000 patients of various tumour sites have been treated with therapeutic carbon-ion beams at the National Institute of Radiological Sciences (NIRS), QST. In carbon-ion radiotherapy treatment planning, the dose distribution in patient must be calculated considering the physics interactions of therapeutic carbon-ion beam with body tissue materials. In addition, the biological effectiveness of the therapeutic beams has to be predicted based on one of biological models. The microdosimetric kinetic (MK) model has been used for this purpose at the NIRS. In my talk, the physics and biological models used in our treatment planning system will be introduced. 

About the speaker： 

Dr. Taku Inaniwa received doctor of science from Tokyo Institute of Technology at 2006. He started his research career of charged-particle therapy since 2006 as a post-doctoral researched at National Institute of Radiological Sciences (NIRS). He is now a group leader of treatment beam research group at Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST) in Japan. His research focuses on developing dose calculation algorithms and biological models used for charged particle therapy treatment planning. In addition, he is also interested in the development of novel treatment methods. 

He has contributed >100 peer reviewed publications. Three of his first author publications have been selected as Highlights from Physics in Medicine and Biology. He is a member of international scientific advisory board of the journal. For his works, he has received several national and international awards.